Varicella Skin Complications in Childhood: A Case Series and a Systematic Review of the Literature
- PMID: 27164095
- PMCID: PMC4881514
- DOI: 10.3390/ijms17050688
Varicella Skin Complications in Childhood: A Case Series and a Systematic Review of the Literature
Abstract
Even if varicella is generally considered a harmless disease in childhood, severe complications may occur. We examined varicella skin complications (VSCs) in hospitalized immunologically healthy children, over a nine-year period. We also systematically analyzed previous reports to calculate the rate of VSCs in the literature. VSCs occurred in 16.4% of children hospitalized for varicella. This figure is in accordance with the literature, as the range of VSCs was 2.6%-41.2%. Skin complications may represent determinants of hospitalization and of other indirect costs in young children.
Keywords: children; hospitalization; skin complication; varicella.
Figures
Similar articles
-
Severe skin complications of varicella in previously healthy children in Iran: emerging concern.BMC Infect Dis. 2025 Mar 24;25(1):402. doi: 10.1186/s12879-025-10794-w. BMC Infect Dis. 2025. PMID: 40128649 Free PMC article.
-
Severe complications of varicella in previously healthy children in Germany: a 1-year survey.Pediatrics. 2001 Nov;108(5):E79. Pediatrics. 2001. PMID: 11694663
-
Don't forget how severe varicella can be--complications of varicella in children in a defined Polish population.Int J Infect Dis. 2013 Jul;17(7):e485-9. doi: 10.1016/j.ijid.2012.11.024. Epub 2013 Jan 23. Int J Infect Dis. 2013. PMID: 23352485
-
Healthcare resource use and costs of varicella and its complications: A systematic literature review.Hum Vaccin Immunother. 2023 Dec 15;19(3):2266225. doi: 10.1080/21645515.2023.2266225. Epub 2023 Oct 27. Hum Vaccin Immunother. 2023. PMID: 37885425 Free PMC article.
-
[Evaluation of varicella complications through a retrospective hospital survey in a paediatric center over 16 years in France].Arch Pediatr. 2004 Sep;11(9):1145-51. doi: 10.1016/j.arcped.2004.07.002. Arch Pediatr. 2004. PMID: 15351011 Review. French.
Cited by
-
Infectious Diseases: Pathophysiology, Diagnostics and Prevention.Int J Mol Sci. 2016 Sep 2;17(9):1464. doi: 10.3390/ijms17091464. Int J Mol Sci. 2016. PMID: 27598145 Free PMC article.
-
The role of vaccines in preventing bacterial antimicrobial resistance.Nat Med. 2018 Jan 9;24(1):10-19. doi: 10.1038/nm.4465. Nat Med. 2018. PMID: 29315295 Review.
-
Secondary Bacterial Infections in Patients with Atopic Dermatitis or Other Common Dermatoses.Am J Clin Dermatol. 2024 Jul;25(4):623-637. doi: 10.1007/s40257-024-00856-1. Epub 2024 Apr 5. Am J Clin Dermatol. 2024. PMID: 38578398 Review.
-
Severe skin complications of varicella in previously healthy children in Iran: emerging concern.BMC Infect Dis. 2025 Mar 24;25(1):402. doi: 10.1186/s12879-025-10794-w. BMC Infect Dis. 2025. PMID: 40128649 Free PMC article.
-
Varicella Zoster Virus Impairs Expression of the Nonclassical Major Histocompatibility Complex Class I-Related Gene Protein (MR1).J Infect Dis. 2023 Feb 1;227(3):391-401. doi: 10.1093/infdis/jiab526. J Infect Dis. 2023. PMID: 34648018 Free PMC article.
References
-
- Liese J.G., Grote V., Rosenfeld E., Fischer R., Belohradsky B.H., Kries R.V., ESPED Varicella Study Group The burden of varicella complications before the introduction of routine varicella vaccination in Germany. Pediatr. Infect. Dis. J. 2008;27:119–124. doi: 10.1097/INF.0b013e3181586665. - DOI - PubMed
-
- Losurdo G., Bertoluzzo L., Canale F., Timitilli A., Bondi E., Castagnola E., Giacchino R. Varicella and its complications as cause of hospitalization. Infez. Med. 2005;13:229–234. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical