Opposing Functions for Plant Xanthine Dehydrogenase in Response to Powdery Mildew Infection: Production and Scavenging of Reactive Oxygen Species

doi:10.1105/tpc.16.00381

Editorial

. 2016 May;28(5):1001.

doi: 10.1105/tpc.16.00381. Epub 2016 May 10.

Opposing Functions for Plant Xanthine Dehydrogenase in Response to Powdery Mildew Infection: Production and Scavenging of Reactive Oxygen Species

Nancy R Hofmann¹

Affiliations

PMID: 27166140
PMCID: PMC4904684
DOI: 10.1105/tpc.16.00381

Editorial

Opposing Functions for Plant Xanthine Dehydrogenase in Response to Powdery Mildew Infection: Production and Scavenging of Reactive Oxygen Species

Nancy R Hofmann. Plant Cell. 2016 May.

. 2016 May;28(5):1001.

doi: 10.1105/tpc.16.00381. Epub 2016 May 10.

Author

Nancy R Hofmann¹

Affiliation

¹ Science Editor nhofmann@aspb.org.

PMID: 27166140
PMCID: PMC4904684
DOI: 10.1105/tpc.16.00381

No abstract available

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Figures

None — XDH1 plays opposing roles to harness ROS in resistance to powdery mildew fungus. In invaded epidermal cells, XDH1 produces superoxide, contributing to the ROS burst that constrains the fungal haustorium. In mesophyll cells, XDH1 produces uric acid to scavenge ROS and protect chloroplasts from oxidative damage. (*Adapted from Figure 9 of* *Ma et al. [2016]*.)

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Comment on

Dual and Opposing Roles of Xanthine Dehydrogenase in Defense-Associated Reactive Oxygen Species Metabolism in Arabidopsis.
Ma X, Wang W, Bittner F, Schmidt N, Berkey R, Zhang L, King H, Zhang Y, Feng J, Wen Y, Tan L, Li Y, Zhang Q, Deng Z, Xiong X, Xiao S. Ma X, et al. Plant Cell. 2016 May;28(5):1108-26. doi: 10.1105/tpc.15.00880. Epub 2016 May 5. Plant Cell. 2016. PMID: 27152019 Free PMC article.

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References

1. Ma X., et al. (2016). Dual and opposing roles of xanthine dehydrogenase in defense-associated reactive oxygen species metabolism in Arabidopsis. Plant Cell 28: 1108–1126. - PMC - PubMed
1. Vorbach C., Harrison R., Capecchi M.R. (2003). Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol. 24: 512–517. - PubMed
1. Zarepour M., Kaspari K., Stagge S., Rethmeier R., Mendel R.R., Bittner F. (2010). Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity. Plant Mol. Biol. 72: 301–310. - PubMed

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[1] Ma X., et al. (2016). Dual and opposing roles of xanthine dehydrogenase in defense-associated reactive oxygen species metabolism in Arabidopsis. Plant Cell 28: 1108–1126. - PMC - PubMed

[2] Ma X., et al. (2016). Dual and opposing roles of xanthine dehydrogenase in defense-associated reactive oxygen species metabolism in Arabidopsis. Plant Cell 28: 1108–1126. - PMC - PubMed

[3] Vorbach C., Harrison R., Capecchi M.R. (2003). Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol. 24: 512–517. - PubMed

[4] Vorbach C., Harrison R., Capecchi M.R. (2003). Xanthine oxidoreductase is central to the evolution and function of the innate immune system. Trends Immunol. 24: 512–517. - PubMed

[5] Zarepour M., Kaspari K., Stagge S., Rethmeier R., Mendel R.R., Bittner F. (2010). Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity. Plant Mol. Biol. 72: 301–310. - PubMed

[6] Zarepour M., Kaspari K., Stagge S., Rethmeier R., Mendel R.R., Bittner F. (2010). Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity. Plant Mol. Biol. 72: 301–310. - PubMed

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Opposing Functions for Plant Xanthine Dehydrogenase in Response to Powdery Mildew Infection: Production and Scavenging of Reactive Oxygen Species

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Opposing Functions for Plant Xanthine Dehydrogenase in Response to Powdery Mildew Infection: Production and Scavenging of Reactive Oxygen Species

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