Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2015 Oct;11(2):158-61.
doi: 10.13004/kjnt.2015.11.2.158. Epub 2015 Oct 31.

Leg Swelling Caused by Heterotopic Ossification Mimicking Deep Vein Thrombosis in a Paraplegic Patient

Affiliations
Case Reports

Leg Swelling Caused by Heterotopic Ossification Mimicking Deep Vein Thrombosis in a Paraplegic Patient

Jin Hyuk Bang et al. Korean J Neurotrauma. 2015 Oct.

Abstract

Leg swelling in patients with paraplegia due to spinal cord injury (SCI) occurs for various reasons, including heterotopic ossification (HO), deep vein thrombosis (DVT), fracture, or cellulitis. The clinical presentations of these conditions may overlap in part or in whole and it may occasionally be difficult to distinguish. Of these conditions, DVT and subsequent pulmonary embolism remain significant causes of morbidity and mortality in patients with SCI. Therefore, a prompt diagnostic work-up, particularly for DVT, is essential in patients with SCI, who present with leg swelling. Here, we report a case of leg swelling in a paraplegic patient, resulting from HO mimicking DVT and discuss the differential diagnosis.

Keywords: Ossification, heterotopic; Paraplegia; Spinal cord injuries; Venous thrombosis.

PubMed Disclaimer

Conflict of interest statement

The authors have no financial conflicts of interest.

Figures

FIGURE 1
FIGURE 1. Computed tomography venography of the lower extremities. A: Coronal source image of venography shows heterotopic ossification (HO) (white arrow) and narrowing of the left external iliac vein (EIV) (black arrow) compared to the right vein (arrowhead). B: Axial source image of venography shows HO (white arrow) located anteromedial to the femur and displaces the iliopsoas muscle anteromedially (asterisk). Narrowing of the diameter of left EIV (black arrow) is noted compared to the right vein (arrowhead). C: Three-dimensional reconstruction image shows HO (white arrows) located anteromedial to the femur. Narrowing of the left EIV (black arrow) compared to the right vein (arrowhead) under the region where the inguinal ligament runs is noted.

References

    1. Aubut JA, Mehta S, Cullen N, Teasell RW ERABI Group; Scire Research Team. A comparison of heterotopic ossification treatment within the traumatic brain and spinal cord injured population: an evidence based systematic review. NeuroRehabilitation. 2011;28:151–160. - PMC - PubMed
    1. Bekou V, Galis D, Traber J. Unilateral leg swelling: deep vein thrombosis? Phlebology. 2011;26:8–13. - PubMed
    1. Blankenship LD, Strommen JA. 27-year-old man with a swollen leg. Mayo Clin Proc. 2000;75:977–980. - PubMed
    1. Chang JH, Lee HJ, Kwon JH, Ryu GH, Moon H, Kim C, et al. Usefulness of the computed tomography venography for evaluation of leg edema including deep vein thrombosis in rehabilitation patients. Ann Rehabil Med. 2014;38:812–820. - PMC - PubMed
    1. Citak M, Suero EM, Backhaus M, Aach M, Godry H, Meindl R, et al. Risk factors for heterotopic ossification in patients with spinal cord injury: a case-control study of 264 patients. Spine (Phila Pa 1976) 2013;37:1953–1957. - PubMed

Publication types

LinkOut - more resources