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Comment
. 2016 May 31;113(22):E3054-6.
doi: 10.1073/pnas.1525116113. Epub 2016 May 12.

Genome of a tardigrade: Horizontal gene transfer or bacterial contamination?

Affiliations
Comment

Genome of a tardigrade: Horizontal gene transfer or bacterial contamination?

Felix Bemm et al. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Fig. 1.
Fig. 1.
(A) Per-site coverage of trusted and untrusted assembly based on mappings of Moleculo reads. Contigs from the untrusted assembly generally don’t share the coverage of the trusted, most likely nuclear, genome. (B) GC content of trusted and untrusted assembly estimated using sliding window approach. The untrusted assembly contains multiple peaks pointing toward contig subpopulations with different GC content. (C) Per-site variability of trusted and untrusted assembly, which can serve as ploidy proxy. The untrusted variability spectrum seems distorted and contains a multitude of different peaks, whereas the trusted assembly shows a typical diploid spectrum. (D) Length distribution of intergenetic regions. Intragenetic regions are significantly larger in the trusted assembly than in the untrusted.
Fig. 2.
Fig. 2.
Circular map of an unknown bacterial genome probably belonging to the Chitinophagaceae drawn with CGView. Tracks 1 and 2 (blue) indicate GeneMark-S annotated genes on forward and reverse strand. Track 3 (red) visualizes regions of homology to a set of 30,844 Chitinophagaceae proteins downloaded from UniProtKB. Track 4 (green) shows homology between GeneMark-S predicted proteins and the published protein set of ref. .

Comment in

Comment on

References

    1. Boothby TC, et al. Evidence for extensive horizontal gene transfer from the draft genome of a tardigrade. Proc Natl Acad Sci USA. 2015;112(52):15976–15981. - PMC - PubMed
    1. Gabriel WN, et al. The tardigrade Hypsibius dujardini, a new model for studying the evolution of development. Dev Biol. 2007;312(2):545–559. - PubMed
    1. Koutsovoulos G, et al. No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini. Proc Natl Acad Sci USA. 2016;113(18):5053–5058. - PMC - PubMed

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