The efficiency of multiparametric magnetic resonance imaging (mpMRI) using PI-RADS Version 2 in the diagnosis of clinically significant prostate cancer

Abstract

Objectives: To investigate the efficiency of multiparametric MRI (mpMRI) based on Prostate Imaging Reporting and Data System (PI-RADS) Version 2 (v2) in detecting clinically significant prostate cancer (PCa) and to test the interobserver consistency.

Methods: Based on PI-RADS v2, two radiologists reviewed the images of 372 patients who underwent prostate biopsy and prebiopsy mpMRI.

Results: There's significant correlation between higher PI-RADS score and the presence of clinical significant PCa (P<.001). PI-RADS score 3 was the best cutoff point with sensitivity and specificity over 80%. The diagnostic concordance was moderate (kappa=0.478).

Conclusions: PI-RADS v2 demonstrated good accuracy in detecting clinically significant PCa, however the interobserver consistency needs to be improved.

Keywords: Diagnosis; Magnetic resonance imaging; Prostate cancer; Sensitivity; Specificity.