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Comment
. 2016 Jun;89(6):1183-5.
doi: 10.1016/j.kint.2016.03.008.

Unlocking the code: mining the urinary proteome after renal transplantation

Zoltan H Endre  1 , Mangalee Fernando  2
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Free article
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Unlocking the code: mining the urinary proteome after renal transplantation

Zoltan H Endre et al. Kidney Int. 2016 Jun.
Free article

Abstract

Diagnosis of transplant dysfunction usually requires kidney biopsy. Sidgel et al. compared urinary proteomics with matched kidney biopsies to develop a biomarker panel to differentiate acute rejection, BK viral nephropathy, and chronic allograft nephropathy. The results suggest that monitoring a panel of urinary peptides may ultimately facilitate noninvasive diagnosis and management of common transplant complications.

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  • Mining the human urine proteome for monitoring renal transplant injury.
    Sigdel TK, Gao Y, He J, Wang A, Nicora CD, Fillmore TL, Shi T, Webb-Robertson BJ, Smith RD, Qian WJ, Salvatierra O, Camp DG 2nd, Sarwal MM. Sigdel TK, et al. Kidney Int. 2016 Jun;89(6):1244-52. doi: 10.1016/j.kint.2015.12.049. Epub 2016 Mar 4. Kidney Int. 2016. PMID: 27165815 Free PMC article.

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