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. 2016 Sep;35(9):979-80.
doi: 10.1097/INF.0000000000001212.

Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

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Cryptococcal Meningitis Presenting as a Complication in HIV-infected Children: A Case Series From Sub-Saharan Africa

Tinashe K Nyazika et al. Pediatr Infect Dis J. 2016 Sep.

Abstract

Cryptococcal meningitis is a leading infectious disease worldwide as a result of the high burden of HIV and AIDS, although its cumulative incidence is very low in children compared with that in adults. Very few studies involving the disease in children have been reported including sub-Saharan Africa, with the highest prevalence of HIV-infected children in the world. We summarize 5 cases of children diagnosed with cryptococcal meningitis at a tertiary hospital in Harare, Zimbabwe, between October 1, 2013, and September 30, 2014.

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Conflict of interest statement

Conflict of Interest: The authors declare no conflict of interest

References

    1. Park BJ, Wannemuehler KA, Marston BJ, Govender N, Pappas PG, Chiller TM. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS. 2009;23:525–30. - PubMed
    1. Miglia KJ, Govender NP, Rossouw J, et al. Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. J Clin Microbiol. 2011;49:307–14. - PMC - PubMed
    1. Meiring ST, Quan VC, Cohen C, et al. A comparison of cases of paediatric-onset and adult-onset cryptococcosis detected through population-based surveillance, 2005-2007. AIDS. 2012;26:2307–14. - PubMed
    1. Gumbo T, Kadzirange G, Mielke J, Gangaidzo IT, Hakim JG. Cryptococcus neoformans meningoencephalitis in African children with acquired immunodeficiency syndrome. Pediatr Infect Dis J. 2002;21:54–6. - PubMed
    1. Lizarazo J, Escandón P, Agudelo CI, Castañeda E. Cryptococcosis in Colombian children and literature review. Inst Oswaldo Cruz. 2014;109:797–804. - PMC - PubMed

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