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Review
. 2016 Jun;50(1 Suppl):21-42.
doi: 10.1177/0023677216642397.

Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 2

Kathy Laber  1 , Christian E Newcomer  2 , Thierry Decelle  3 , Jeffrey I Everitt  4 , Javier Guillen  5 , Aurora Brønstad  6
Affiliations
Review

Recommendations for Addressing Harm-Benefit Analysis and Implementation in Ethical Evaluation - Report from the AALAS-FELASA Working Group on Harm-Benefit Analysis - Part 2

Kathy Laber et al. Lab Anim. 2016 Jun.

Abstract

International regulations and guidelines strongly suggest that the use of animal models in scientific research should be initiated only after the authority responsible for the review of animal studies has concluded a well-thought-out harm-benefit analysis (HBA) and deemed the project to be appropriate. The AALAS-FELASA working group on HBA has performed a literature review and based on this review, proposed a method for HBA. Examples of the working group's approach are included in this report.

Keywords: ethical review; harm–benefit.

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References

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    1. Garber JC, Barbee RW, Bielitzki JT, et al., Committee for the Update of the Guide for the Care and Use of Laboratory Animals (eds) Guide for the care and use of laboratory animals. 8th edn. Washington DC: National Academies Press, 2011.

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