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Review
. 2016 Jul;61(4):347-58.
doi: 10.1007/s12223-016-0462-y. Epub 2016 May 18.

Biogenesis of antibiotics-viewing its history and glimpses of the future

J Spížek  1 , K Sigler  2 , T Řezanka  2 , A Demain  3
Affiliations
Review

Biogenesis of antibiotics-viewing its history and glimpses of the future

J Spížek et al. Folia Microbiol (Praha). 2016 Jul.

Abstract

This review aims at comparing some historical data with the current situation in the study of biogenesis of natural compounds, antibiotics in the first place. Biogenesis of tetracyclines and cycloheximide and related compounds serves as example. Examples of molecular biological and bioinformatics methods used in the study of antibiotic biogenesis are described both in terms of its historical aspects and the current knowledge.

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References

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