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. 2016 Jun 1;62 Suppl 4(Suppl 4):S314-7.
doi: 10.1093/cid/ciw092.

Hepatitis B in Pregnancy

Tram T Tran  1
Affiliations

Hepatitis B in Pregnancy

Tram T Tran. Clin Infect Dis. .

Abstract

Chronic hepatitis B virus (HBV) infection is estimated to affect >350 million people worldwide and represents a significant cause of morbidity and mortality related to cirrhosis and hepatocellular carcinoma. Mother-to-child transmission (MTCT) of HBV remains an important source of incident cases of HBV. Current barriers to eradication of incident HBV infections via MTCT include underutilization of immunoprophylaxis with hepatitis B vaccination and hepatitis B immune globulin in certain endemic regions as well as failure of immunoprophylaxis.

Keywords: hepatitis B; perinatal transmission; pregnancy; vaccination HBIG.

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Figures

Figure 1.
Figure 1.
Suggested management strategy for hepatitis B surface antigen (HBsAg)–positive women in pregnancy. Abbreviations: 3TC, lamivudine; anti-HBc, hepatitis B core antibody; anti-HBs, hepatitis B surface antibody; HBIG, hepatitis B immune globulin; HBs, hepatitis B surface; HBV, hepatitis B virus; TBV, telbivudine; TDF, tenofovir disoproxil fumarate.
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