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. 2016 Jun;22(6):1127-9.
doi: 10.3201/eid2206.152051.

Next-Generation Sequencing of Mycobacterium tuberculosis

Igor Mokrousov, Ekaterina Chernyaeva, Anna Vyazovaya, Viacheslav Sinkov, Viacheslav Zhuravlev, Olga Narvskaya

Next-Generation Sequencing of Mycobacterium tuberculosis

Igor Mokrousov et al. Emerg Infect Dis. 2016 Jun.
No abstract available

Keywords: Mycobacterium tuberculosis; bacteria; next-generation sequencing; spoligotyping; tuberculosis and other mycobacteria; whole-genome sequencing.

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Figures

Figure
Figure
A) Spoligotyping hybridization profiles of H37Rv and BCG reference strains, Mycobacterium tuberculosis SIT266 (2 strains in this study) and SIT264 (previously published strain in [3]). SIT, spoligotype international type, designated according to SITVIT_WEB database (http://www.pasteur-guadeloupe.fr:8081/SITVIT_ONLINE). B) Schematic view of the DR/CRISPR locus (region of spacers 7–9) in spoligotypes SIT264 and SIT266 and reference strain H37Rv, inferred from next-generation sequencing data. Reverse DRa primer is biotin-labeled. IS6110 is not to scale.
See this image and copyright information in PMC

References

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    1. Mokrousov I, Vyazovaya A, Solovieva N, Sunchalina T, Markelov Y, Chernyaeva E, et al. Trends in molecular epidemiology of drug-resistant tuberculosis in Republic of Karelia, Russian Federation. BMC Microbiol. 2015;15:279. 10.1186/s12866-015-0613-3 - DOI - PMC - PubMed

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