Drug discovery: Fighting evolution with chemical synthesis
- PMID: 27193674
- DOI: 10.1038/533326a
Drug discovery: Fighting evolution with chemical synthesis
Comment on
-
A platform for the discovery of new macrolide antibiotics.Nature. 2016 May 19;533(7603):338-45. doi: 10.1038/nature17967. Nature. 2016. PMID: 27193679 Free PMC article.
Similar articles
-
A platform for the discovery of new macrolide antibiotics.Nature. 2016 May 19;533(7603):338-45. doi: 10.1038/nature17967. Nature. 2016. PMID: 27193679 Free PMC article.
-
Synthesis and antibacterial activity of novel bifunctional macrolides.Bioorg Med Chem Lett. 2004 Jul 16;14(14):3809-13. doi: 10.1016/j.bmcl.2004.04.077. Bioorg Med Chem Lett. 2004. PMID: 15203167
-
New Insights into the Synthesis and Biological Activity of the Pamamycin Macrodiolides.Chimia (Aarau). 2016;70(1-2):20-8. doi: 10.2533/chimia.2016.20. Chimia (Aarau). 2016. PMID: 26931213 Review.
-
Synthesis and biological activity of 4''-O-acyl derivatives of 14- and 15-membered macrolides linked to omega-quinolone-carboxylic unit.Bioorg Med Chem. 2010 Sep 1;18(17):6547-58. doi: 10.1016/j.bmc.2010.06.050. Epub 2010 Jun 22. Bioorg Med Chem. 2010. PMID: 20621489
-
Macrolide Hybrid Compounds: Drug Discovery Opportunities in Anti- Infective and Anti-inflammatory Area.Curr Top Med Chem. 2017;17(8):919-940. doi: 10.2174/1568026616666160927160036. Curr Top Med Chem. 2017. PMID: 27697049 Review.
Cited by
-
Single-step retrosynthesis prediction via multitask graph representation learning.Nat Commun. 2025 Jan 18;16(1):814. doi: 10.1038/s41467-025-56062-y. Nat Commun. 2025. PMID: 39827189 Free PMC article.
References
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical