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Case Reports
. 2016 Jan-Apr;20(1):164.
doi: 10.4103/0973-029X.180986.

Role of inflammation in developmental odontogenic pathosis

Sandeep S Gupta  1 , Devi C Shetty  2 , Aadithya B Urs  3 , P Nainani  1
Affiliations
Case Reports

Role of inflammation in developmental odontogenic pathosis

Sandeep S Gupta et al. J Oral Maxillofac Pathol. 2016 Jan-Apr.

Abstract

Periapical infection in the primary tooth may lead to periapical abscess, granuloma, radicular cyst and even osteomyelitis. The infection in primary teeth can also affect the developing successor teeth leading to hypomineralization, hypoplasia, arrest of tooth development, regional odontodysplasia, delayed eruption etc. The purpose of this article is to report a case of malformed permanent tooth in relation to overlying infected deciduous teeth. The probable role of inflammation in pathogenesis of the present condition is also being discussed.

Keywords: Deciduous teeth; inflammation; malformed teeth; matrix metaloproteinases; radicular cyst.

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Figures

Figure 1
Figure 1
Photograph showing extraoral swelling on left cheek region of the face
Figure 2
Figure 2
Orthopantomogram shows a well-defined unilocular radiolucent lesion extending from the mesial surface of 63 to the unerupted 26, absence of developing tooth bud of 24 and 25, oval radio-opacity (arrow). Intraoral periapical in the inset shows grossly carious 64 and 65
Figure 3
Figure 3
Photograph showing gross specimen consisting of (a) inset showing cystic lining, (b) crypt-like malformed tooth structure, (c) malformed tooth covered by portion of cystic lining
Figure 4
Figure 4
Photomicrograph showing cystic cavity lined by nonkeratinized stratified squamous epithelium showing arcading pattern (H&E stain, ×40)
Figure 5
Figure 5
Photomicrograph showing longitudinally arranged dentinal tubules in the ground section (Ground section, ×40) and inset showing dentinal tubules in decalcified section (H&E stain, ×200)
Figure 6
Figure 6
Photomicrograph showing an arrangement resembling dentinal tubules merging with haversian canal (H&E stain, ×100)
Figure 7
Figure 7
Photomicrograph showing lamellar bone pattern (ground section, ×200)
Figure 8
Figure 8
Photomicrograph showing odontogenic epithelium with presence of columnar ciliated cells (H&E stain, ×100)
See this image and copyright information in PMC

References

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