Stool frequency is associated with gut microbiota composition

Fatemeh Hadizadeh^{1

2}, Susanna Walter³, Meriem Belheouane^{4

5}, Ferdinando Bonfiglio¹, Femke-Anouska Heinsen⁶, Anna Andreasson^{7

8}, Lars Agreus⁷, Lars Engstrand^{9

10}, John F Baines^{4

5}, Joseph Rafter¹, Andre Franke⁶, Mauro D'Amato^{1

11}

Affiliations

¹ Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
² School of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran.
³ Division of Gastroenterology, Institution of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
⁴ Max Planck Institute for Evolutionary Biology, Plön, Germany.
⁵ Institute for Experimental Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany.
⁶ Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
⁷ Division for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
⁸ Stress Research Institute, Stockholm University, Stockholm, Sweden.
⁹ Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
¹⁰ Clinical Genomics Facility, Science for Life Laboratory, Stockholm, Sweden.
¹¹ BioCruces Health Research Institute and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

Comment

Fatemeh Hadizadeh et al. Gut. 2017 Mar.

. 2017 Mar;66(3):559-560.

doi: 10.1136/gutjnl-2016-311935. Epub 2016 Apr 28.

¹ Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
² School of Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran.
³ Division of Gastroenterology, Institution of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.
⁴ Max Planck Institute for Evolutionary Biology, Plön, Germany.
⁵ Institute for Experimental Medicine, Christian-Albrechts-University of Kiel, Kiel, Germany.
⁶ Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.
⁷ Division for Family Medicine, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.
⁸ Stress Research Institute, Stockholm University, Stockholm, Sweden.
⁹ Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
¹⁰ Clinical Genomics Facility, Science for Life Laboratory, Stockholm, Sweden.
¹¹ BioCruces Health Research Institute and IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

No abstract available

Keywords: GASTROINTESTINAL TRANSIT; INTESTINAL BACTERIA.

Comment in

A GWAS meta-analysis suggests roles for xenobiotic metabolism and ion channel activity in the biology of stool frequency.
Jankipersadsing SA, Hadizadeh F, Bonder MJ, Tigchelaar EF, Deelen P, Fu J, Andreasson A, Agreus L, Walter S, Wijmenga C, Hysi P, D'Amato M, Zhernakova A. Jankipersadsing SA, et al. Gut. 2017 Apr;66(4):756-758. doi: 10.1136/gutjnl-2016-312398. Epub 2016 Jul 29. Gut. 2017. PMID: 27473416 Free PMC article. No abstract available.

Stool consistency is strongly associated with gut microbiota richness and composition, enterotypes and bacterial growth rates.
Vandeputte D, Falony G, Vieira-Silva S, Tito RY, Joossens M, Raes J. Vandeputte D, et al. Gut. 2016 Jan;65(1):57-62. doi: 10.1136/gutjnl-2015-309618. Epub 2015 Jun 11. Gut. 2016. PMID: 26069274 Free PMC article.
Gut microbiota composition associated with stool consistency.
Tigchelaar EF, Bonder MJ, Jankipersadsing SA, Fu J, Wijmenga C, Zhernakova A. Tigchelaar EF, et al. Gut. 2016 Mar;65(3):540-2. doi: 10.1136/gutjnl-2015-310328. Epub 2015 Aug 14. Gut. 2016. PMID: 26276682 No abstract available.