Physiological changes in pregnancy

doi:10.5830/CVJA-2016-021

Review

. 2016 Mar-Apr;27(2):89-94.

doi: 10.5830/CVJA-2016-021.

Physiological changes in pregnancy

Priya Soma-Pillay¹, Catherine Nelson-Piercy², Heli Tolppanen³, Alexandre Mebazaa⁴

Affiliations

¹ Department of Obstetrics and Gynaecology, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa. Email: Priya.Soma-Pillay@up.ac.za.
² Department of Obstetric Medicine, Women's Health Academic Centre, King's Health Partners; Guy's and St Thomas' Foundation Trust, and Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare Trust, London, UK.
³ INSERM UMRS 942, Paris, France.
⁴ INSERM UMRS 942, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Paris; Department of Anesthesia and Critical Care, Hôpital Lariboisière, APHP, France.

PMID: 27213856
PMCID: PMC4928162
DOI: 10.5830/CVJA-2016-021

Review

Physiological changes in pregnancy

Priya Soma-Pillay et al. Cardiovasc J Afr. 2016 Mar-Apr.

. 2016 Mar-Apr;27(2):89-94.

doi: 10.5830/CVJA-2016-021.

Authors

Priya Soma-Pillay¹, Catherine Nelson-Piercy², Heli Tolppanen³, Alexandre Mebazaa⁴

Affiliations

¹ Department of Obstetrics and Gynaecology, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa. Email: Priya.Soma-Pillay@up.ac.za.
² Department of Obstetric Medicine, Women's Health Academic Centre, King's Health Partners; Guy's and St Thomas' Foundation Trust, and Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare Trust, London, UK.
³ INSERM UMRS 942, Paris, France.
⁴ INSERM UMRS 942, Paris, France; University Paris Diderot, Sorbonne Paris Cité, Paris; Department of Anesthesia and Critical Care, Hôpital Lariboisière, APHP, France.

PMID: 27213856
PMCID: PMC4928162
DOI: 10.5830/CVJA-2016-021

Abstract

Physiological changes occur in pregnancy to nurture the developing foetus and prepare the mother for labour and delivery. Some of these changes influence normal biochemical values while others may mimic symptoms of medical disease. It is important to differentiate between normal physiological changes and disease pathology. This review highlights the important changes that take place during normal pregnancy.

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Figures

**Fig. 1.**
Physiological changes in respiratory function in pregnancy.

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References

1. Locktich G. Clinical biochemistry of pregnancy. Crit Rev Clin Lab Sci. 1997;34:6. - PubMed
1. Rodger M, Sheppard D, Gandara E, Tinmouth A. Haematological problems in obstetrics. Best Prac Res Clin Obstet Gynaecol. 2015;29(5):671–684. - PubMed
1. Ramsay M. The Obstetric Hematology Manual. Cambridge:: Cambridge University Press; 2010. Normal hematological changes during pregnancy and the puerperium. In Pavord S, Hunt B (ed). pp. 3–12.
1. Wilson M, Morganti AA, Zervoudakis I, Letcher RL, Romney BM, Von Oeyon P. et al. Blood pressure, the renin-aldosterone system and sex steroids throughout normal pregnancy. Am J Med. 1980;68(1):97–104. - PubMed
1. Davison JM. Renal haemodynamics and volume homeostasis in pregnancy. Scand J Clin Lab Invest Suppl. 1984;169:15–27. - PubMed

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[1] Locktich G. Clinical biochemistry of pregnancy. Crit Rev Clin Lab Sci. 1997;34:6. - PubMed

[2] Locktich G. Clinical biochemistry of pregnancy. Crit Rev Clin Lab Sci. 1997;34:6. - PubMed

[3] Rodger M, Sheppard D, Gandara E, Tinmouth A. Haematological problems in obstetrics. Best Prac Res Clin Obstet Gynaecol. 2015;29(5):671–684. - PubMed

[4] Rodger M, Sheppard D, Gandara E, Tinmouth A. Haematological problems in obstetrics. Best Prac Res Clin Obstet Gynaecol. 2015;29(5):671–684. - PubMed

[5] Ramsay M. The Obstetric Hematology Manual. Cambridge:: Cambridge University Press; 2010. Normal hematological changes during pregnancy and the puerperium. In Pavord S, Hunt B (ed). pp. 3–12.

[6] Ramsay M. The Obstetric Hematology Manual. Cambridge:: Cambridge University Press; 2010. Normal hematological changes during pregnancy and the puerperium. In Pavord S, Hunt B (ed). pp. 3–12.

[7] Wilson M, Morganti AA, Zervoudakis I, Letcher RL, Romney BM, Von Oeyon P. et al. Blood pressure, the renin-aldosterone system and sex steroids throughout normal pregnancy. Am J Med. 1980;68(1):97–104. - PubMed

[8] Wilson M, Morganti AA, Zervoudakis I, Letcher RL, Romney BM, Von Oeyon P. et al. Blood pressure, the renin-aldosterone system and sex steroids throughout normal pregnancy. Am J Med. 1980;68(1):97–104. - PubMed

[9] Davison JM. Renal haemodynamics and volume homeostasis in pregnancy. Scand J Clin Lab Invest Suppl. 1984;169:15–27. - PubMed

[10] Davison JM. Renal haemodynamics and volume homeostasis in pregnancy. Scand J Clin Lab Invest Suppl. 1984;169:15–27. - PubMed

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Physiological changes in pregnancy

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