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Review
. 2016 Jul;27(7):441-442.
doi: 10.1016/j.tem.2016.05.002. Epub 2016 May 20.

Mitochondria-Power Players in Kidney Function?

Josephine M Forbes  1
Affiliations
Review

Mitochondria-Power Players in Kidney Function?

Josephine M Forbes. Trends Endocrinol Metab. 2016 Jul.

Abstract

A recent study has highlighted the relationship between mitochondrial ATP generation and protection against organ injury following ischaemia-reperfusion injury in the kidney. Kidneys are fuel-hungry organs and only second to the heart in mitochondrial number and oxygen consumption. This article speculates on why this might be so.

Keywords: PGC1α; kidney injury; nephropathy; nicotinamide; oxidative phosphorylation.

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