Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016;33(4):343-50.
doi: 10.1159/000445020. Epub 2016 May 25.

Treatment of Locally Advanced Pancreatic Ductal Adenocarcinoma

Andrew P Loehrer  1 , Cristina R Ferrone
Affiliations
Review

Treatment of Locally Advanced Pancreatic Ductal Adenocarcinoma

Andrew P Loehrer et al. Dig Surg. 2016.

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is increasingly common and a leading cause of cancer-related mortality. Surgery remains the only possibility for cure. Upwards of 40% of patients present with locally advanced PDAC (LA-PDAC), where management strategies continue to evolve. In this review, we highlight current trends in neoadjuvant chemotherapy, surgical resection, and other multimodality approaches for patients with LA-PDAC. Despite promising early results, additional work is needed to more accurately and appropriately tailor treatment for patients with LA-PDAC.

PubMed Disclaimer

MeSH terms