Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016:5:81-88.
doi: 10.1007/s13669-016-0162-2. Epub 2016 Apr 25.

Fibroids and Infertility

Affiliations
Review

Fibroids and Infertility

P Purohit et al. Curr Obstet Gynecol Rep. 2016.

Abstract

The precise impact of fibroids, which are the most common benign gynaecological tumours in women, on reproductive function and infertility is unknown. The need to treat submucosal fibroids is widely accepted, but fibroids in other locations and sizes continue to present a clinical conundrum. This article examines the mechanisms by which fibroids affect implantation and fertility, and stratifies their impact on basis of size, location and nature. It also explores the evidence base of the available treatment modalities in specific relation to improving fertility outcomes. Traditionally, a myomectomy has been advocated to treat fibroids for the reproductive population; however, as well as evaluating the benefits of surgery including endoscopic, this article explores alternative therapies including medical and radiological interventions.

Keywords: Fibroids; Implantation; Infertility; Laparoscopy; Miscarriage; Myomectomy.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Overview of investigations and treatment of infertility (adapted with permission from Yalandu and Narvekar, Wiley publishing) [28]

Similar articles

Cited by

References

    1. Elugwaraonu O, Okojie AIO, Okhia O, Oyadoghan GP. The incidence of uterine fibroid among reproductive age women. IJBAIR. 2013;2(3):55–60.
    1. ASRM Practise Committee Myomas and reproductive function. Fertil Steril. 2006;86:S194–S199. - PubMed
    1. Lyons EA, Taylor PJ, Zheng XH, Ballard G, Levi CS, Kredentser JV. Characterization of subendometrial myometrial contractions throughout the menstrual cycle in normal fertile women. Fertil Steril. 1991;55:771–774. doi: 10.1016/S0015-0282(16)54246-0. - DOI - PubMed
    1. Richards PA, Richards PD, Tiltman AJ. The ultrastructure of fibromyomatous myometrium and its relationship to infertility. Hum Reprod Update. 1998;4:520–525. doi: 10.1093/humupd/4.5.520. - DOI - PubMed
    1. Rackow BW, Taylor HS. Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity. Fertil Steril. 2010;93:2027–2034. doi: 10.1016/j.fertnstert.2008.03.029. - DOI - PMC - PubMed