Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989;227(2):139-41.
doi: 10.1007/BF02169786.

Influence of artificial tears on corneal epithelium in dry-eye syndrome

M Göbbels  1 , M Spitznas
Affiliations

Influence of artificial tears on corneal epithelium in dry-eye syndrome

M Göbbels et al. Graefes Arch Clin Exp Ophthalmol. 1989.

Abstract

The corneal epithelium of patients with dry-eye syndrome is stressed by both tear film insufficiency and the frequent use of eye drops (artificial tears). In order to quantify corneal epithelial damage, the permeability of corneal epithelium to sodium fluorescein was determined in 40 consecutive patients with dry eyes (BST less than 10 mm), who did not exhibit visible corneal lesions upon slit-lamp examination. The corneal epithelial permeability of dry-eye patients was shown to be 2.8 times greater than that of individuals without ocular disease. Corneal epithelial permeability of patients using artificial tears containing benzalkonium chloride was increased 3.1 times and that of patients using drops preserved with chlorobutanol only 1.7 times.

PubMed Disclaimer

References

    1. Invest Ophthalmol. 1976 Apr;15(4):246-59 - PubMed
    1. Klin Monbl Augenheilkd. 1986 Sep;189(3):254-7 - PubMed
    1. Invest Ophthalmol. 1967 Oct;6(5):464-77 - PubMed
    1. Surv Ophthalmol. 1980 Jul-Aug;25(1):15-30 - PubMed