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Review
. 2016 Jul 18;55(30):8528-34.
doi: 10.1002/anie.201602159. Epub 2016 May 24.

The Intrinsic Fragility of DNA (Nobel Lecture)

Tomas Lindahl  1
Affiliations
Review

The Intrinsic Fragility of DNA (Nobel Lecture)

Tomas Lindahl. Angew Chem Int Ed Engl. .

Abstract

Our cells contain common molecules, such as water or oxygen, that can damage DNA. In his studies Tomas Lindahl has shown how specific repair enzymes remove and replace damaged parts of DNA in a process of vital importance.

Keywords: DNA repair; Nobel lecture; base mismatch; repair enzymes.

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