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. 1989 May;82(2):131-3.
doi: 10.1007/BF00284044.

A linkage group with FRA16B (the fragile site at 16q22.1)

J C Mulley  1 , V J Hyland, A Fratini, L J Bates, A K Gedeon, G R Sutherland
Affiliations

A linkage group with FRA16B (the fragile site at 16q22.1)

J C Mulley et al. Hum Genet. 1989 May.

Abstract

Polymorphic DNA markers located in bands 16q13, 16q21 and 16q22 were examined for recombination with FRA16B, the fragile site at 16q22.100. A tight linkage cluster D16S10-FRA16B-D16S4-HP was established. There were no recombinants (theta = 0.0, z = 8.3) between D16S10 and D16S4, which flank FRA16B. The markers D16S10 and D16S4 are in close proximity on the genetic map and delineate a small chromosomal segment, which contains the distamycin A-inducible fragile site.

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