DYRK1A: A Promising Drug Target for Islet Transplant-Based Diabetes Therapies

Affiliations

¹ Institute for Beta Cell Biology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research, and German Center for Diabetes Research (DZD e.V.), Düsseldorf, Germany.
² Institute for Beta Cell Biology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research, and German Center for Diabetes Research (DZD e.V.), Düsseldorf, Germany Institute for Metabolic Physiology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany lammert@hhu.de.

Comment

Bengt-Frederik Belgardt et al. Diabetes. 2016 Jun.

. 2016 Jun;65(6):1496-8.

doi: 10.2337/dbi16-0013.

¹ Institute for Beta Cell Biology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research, and German Center for Diabetes Research (DZD e.V.), Düsseldorf, Germany.
² Institute for Beta Cell Biology, German Diabetes Center (DDZ), Leibniz Center for Diabetes Research, and German Center for Diabetes Research (DZD e.V.), Düsseldorf, Germany Institute for Metabolic Physiology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany lammert@hhu.de.

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Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.
Dirice E, Walpita D, Vetere A, Meier BC, Kahraman S, Hu J, Dančík V, Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, Wagner BK. Dirice E, et al. Diabetes. 2016 Jun;65(6):1660-71. doi: 10.2337/db15-1127. Epub 2016 Mar 7. Diabetes. 2016. PMID: 26953159 Free PMC article.