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Review
. 2016 May 26;12(5):e1006004.
doi: 10.1371/journal.pgen.1006004. eCollection 2016 May.

Genomic Imprinting: A New Epigenetic Perspective of Sleep Regulation

Valter Tucci  1
Affiliations
Review

Genomic Imprinting: A New Epigenetic Perspective of Sleep Regulation

Valter Tucci. PLoS Genet. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author has declared that no competing interests exist.

Figures

Fig 1
Fig 1. Evolution of REM sleep and genomic imprinting.
The timeline (expressed as millions of years ago, MYA) on the horizontal axis maps geological and glacial periods and the evolutionary divergence that occurred among reptiles, birds, and mammals (monotremes, eutherians, and marsupials). The red line delineates the presence of genomic imprinting in therians. A description of REM sleep according to different species is annotated on the right.
See this image and copyright information in PMC

References

    1. Archer SN, Oster H. How sleep and wakefulness influence circadian rhythmicity: effects of insufficient and mistimed sleep on the animal and human transcriptome. J Sleep Res. 2015;24(5):476–93. 10.1111/jsr.12307 . - DOI - PubMed
    1. Maret S, Dorsaz S, Gurcel L, Pradervand S, Petit B, Pfister C, et al. Homer1a is a core brain molecular correlate of sleep loss. Proc Natl Acad Sci U S A. 2007;104(50):20090–5. 10.1073/pnas.0710131104 - DOI - PMC - PubMed
    1. Massart R, Freyburger M, Suderman M, Paquet J, El Helou J, Belanger-Nelson E, et al. The genome-wide landscape of DNA methylation and hydroxymethylation in response to sleep deprivation impacts on synaptic plasticity genes. Transl Psychiatry. 2014;4:e347 10.1038/tp.2013.120 - DOI - PMC - PubMed
    1. Azzi A, Dallmann R, Casserly A, Rehrauer H, Patrignani A, Maier B, et al. Circadian behavior is light-reprogrammed by plastic DNA methylation. Nat Neurosci. 2014;17(3):377–82. 10.1038/nn.3651 . - DOI - PubMed
    1. Mignot E. Why we sleep: the temporal organization of recovery. PLoS Biol. 2008;6(4):e106 10.1371/journal.pbio.0060106 - DOI - PMC - PubMed