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Comment
. 2016 May 27;18(6):593-4.
doi: 10.1038/ncb3367.

Replicating repetitive DNA

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Replicating repetitive DNA

Silvia Tognetti et al. Nat Cell Biol. .
Free article

Abstract

The function and regulation of repetitive DNA, the 'dark matter' of the genome, is still only rudimentarily understood. Now a study investigating DNA replication of repetitive centromeric chromosome segments has started to expose a fascinating replication program that involves suppression of ATR signalling, in particular during replication stress.

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References

    1. Biochem Soc Trans. 2013 Dec;41(6):1706-11 - PubMed
    1. Cell. 2013 Nov 21;155(5):1088-103 - PubMed
    1. Chromosoma. 2015 Mar;124(1):13-26 - PubMed
    1. Annu Rev Biochem. 2010;79:89-130 - PubMed
    1. PLoS Genet. 2015 Dec 18;11(12):e1005719 - PubMed

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