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Comment
. 2016 May 27;48(6):591-2.
doi: 10.1038/ng.3579.

DNA-sequence-specific erasers of epigenetic memory

Iva Mozgova  1 , Claudia Köhler  1
Affiliations
Comment

DNA-sequence-specific erasers of epigenetic memory

Iva Mozgova et al. Nat Genet. .

Abstract

How epigenetic regulators find their specific targets remains a challenging question. Two parallel studies show that REF6, a plant H3K27me3 demethylase, binds a specific DNA motif via its zinc-finger domains and recruits the SWI/SNF-type ATPase BRAHMA, demonstrating a sequence-specific recruitment mechanism for a chromatin-modifying complex.

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References

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