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Comment
. 2016 Jul;12(7):378-80.
doi: 10.1038/nrendo.2016.79. Epub 2016 May 27.

Genetics: Healthy ageing, the genome and the environment

Kaare Christensen  1 , Matt McGue  2
Affiliations
Comment

Genetics: Healthy ageing, the genome and the environment

Kaare Christensen et al. Nat Rev Endocrinol. 2016 Jul.

Abstract

The sequenced genomes of individuals aged ≥ 80 years, who were highly educated, self referred volunteers and with no self reported chronic diseases were compared to young controls. In these data, healthy ageing is a distinct phenotype from exceptional longevity and genetic factors that protect against disease might be enriched in this population.

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Conflict of interest statement

Competing interests statement

The authors declare no competing interests.

Comment on

  • Whole-Genome Sequencing of a Healthy Aging Cohort.
    Erikson GA, Bodian DL, Rueda M, Molparia B, Scott ER, Scott-Van Zeeland AA, Topol SE, Wineinger NE, Niederhuber JE, Topol EJ, Torkamani A. Erikson GA, et al. Cell. 2016 May 5;165(4):1002-11. doi: 10.1016/j.cell.2016.03.022. Epub 2016 Apr 21. Cell. 2016. PMID: 27114037 Free PMC article.

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