Erythropoietin in ophthalmology: A literature review
- PMID: 27239595
- PMCID: PMC4881220
- DOI: 10.1016/j.joco.2016.01.008
Erythropoietin in ophthalmology: A literature review
Abstract
Purpose: To review the current literature on ocular application of erythropoietin (EPO).
Methods: A comprehensive search was performed on Pubmed and Scopus databases. All selected articles were reviewed thoroughly by the authors to review current applications of the EPO in ocular diseases.
Results: Various aspects of administration of EPO for different ischemic, traumatic, vascular, and degenerative disorders have been explained. The articles are generally preclinical with few small studies reporting clinical outcomes.
Conclusion: EPO has been used for the treatment of different ophthalmic conditions with promising results. Further studies are needed to elaborate the role of EPO in management of ocular diseases.
Keywords: Apoptosis; Erythropoietin; Neuroprotection.
References
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- Fried W., Kilbridge T., Krantz S., McDonald T.P., Lange R.D. Studies on extrarenal erythropoietin. J Lab Clin Med. 1969;73:244–248. - PubMed
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- Bogoyevitch Marie A. An update on the cardiac effects of erythropoietin cardioprotection by erythropoietin and the lessons learnt from studies in neuroprotection. Cardiovasc Research. 2004;63:208–216. - PubMed
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