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. 1977 Oct;56(10):1285-90.
doi: 10.1177/00220345770560103401.

A method for the in vitro toxicity testing of dental restorative materials

A method for the in vitro toxicity testing of dental restorative materials

M J Tyas. J Dent Res. 1977 Oct.

Abstract

An vitro method of toxicity testing of dental restorative materials is described in which their clinical usage is closely simulated. The test material was separated from the cells by either a synthetic filter or dentine slice. Toxic effects were quantiated by determining changes in enzyme activity by scanning and integrating microdensitometry.

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