Reversible skeletal muscle damage after administration of local anesthetics with and without epinephrine
- PMID: 272451
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Reversible skeletal muscle damage after administration of local anesthetics with and without epinephrine
J Oral Surg.
1978 Mar.
Abstract
Local anesthetic preparations with and without epinephrine, which are in common clinical use, produced reversible skeletal muscle damage in the rat after a single local administration. In addition, epinephrine alone, in concentrations of more than 1:200,000, caused similar but less extensive damage.
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