Screening for ALK Rearrangements in Lung Cancer: Time for a New Generation of Diagnostics?
- PMID: 27245570
- PMCID: PMC4912373
- DOI: 10.1634/theoncologist.2016-0179
Screening for ALK Rearrangements in Lung Cancer: Time for a New Generation of Diagnostics?
Abstract
A study reported in this issue of The Oncologist examined the utility of next-generation sequencing (NGS) in detecting ALK rearrangements. NGS may one day become the standard initial test for molecular genotyping of patients with advanced cancers, and this new generation of ALK diagnostics is a welcome addition to the current screening repertoire.
Conflict of interest statement
Disclosures of potential conflicts of interest may be found at the end of this article.
Comment on
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Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.Oncologist. 2016 Jun;21(6):762-70. doi: 10.1634/theoncologist.2015-0497. Epub 2016 May 31. Oncologist. 2016. PMID: 27245569 Free PMC article.
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