Editorial
doi: 10.1080/15384101.2016.1191257.
Epub 2016 May 31.
HPV-mediated inactivation of tumor suppressor p53
Affiliations
- PMID: 27245825
- PMCID: PMC5004678
- DOI: 10.1080/15384101.2016.1191257
Item in Clipboard
Editorial
HPV-mediated inactivation of tumor suppressor p53
Cell Cycle.
2016 Sep.
No abstract available
Keywords: HPV E6; oncogenic viruses; p53; structure.
Figures
(Top) Ribbon representation of the HPV16 E6/e6ap/p53core ternary complex. Gold: HPV16 E6; green: e6ap; purple: p53core. (Middle) Surface representation of HPV16 E6 colored for residues at the interface with e6ap (green), p53 (purple) and e6ap and p53 (gray). E6N and E6C: N- and C-terminal zinc-binding domains; HL: helix linker. (Bottom) Surface representation of p53core colored for residues at the interface with HPV E6 (gold), DNA (cyan) and SV40 LTag (pink).
Comment on
- doi: 10.1038/nature16481
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