Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2016 Sep;15(17):2231-2.
doi: 10.1080/15384101.2016.1191257. Epub 2016 May 31.

HPV-mediated inactivation of tumor suppressor p53

Gilles Travé  1 , Katia Zanier  2
Affiliations
Editorial

HPV-mediated inactivation of tumor suppressor p53

Gilles Travé et al. Cell Cycle. 2016 Sep.
No abstract available

Keywords: HPV E6; oncogenic viruses; p53; structure.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
(Top) Ribbon representation of the HPV16 E6/e6ap/p53core ternary complex. Gold: HPV16 E6; green: e6ap; purple: p53core. (Middle) Surface representation of HPV16 E6 colored for residues at the interface with e6ap (green), p53 (purple) and e6ap and p53 (gray). E6N and E6C: N- and C-terminal zinc-binding domains; HL: helix linker. (Bottom) Surface representation of p53core colored for residues at the interface with HPV E6 (gold), DNA (cyan) and SV40 LTag (pink).
See this image and copyright information in PMC

Comment on

  • doi: 10.1038/nature16481

References

    1. Levine AJ. Virology 2009; 384:285-93; PMID:19081592; http://dx.doi.org/10.1016/j.virol.2008.09.034 - DOI - PubMed
    1. Werness BA, et al.. Science 1990; 248:76-79; PMID:2157286; - PubMed
    1. Ansari T, et al.. J Virol 2012; 20:11386-91; PMID:22896608; - PMC - PubMed
    1. Zanier K, et al.. Structure 2012; 20:604-17; PMID:22483108; http://dx.doi.org/10.1016/j.str.2012.02.001 - DOI - PMC - PubMed
    1. Zanier K, et al.. Science 2013; 339:694-8; PMID:23393263; http://dx.doi.org/10.1126/science.1229934 - DOI - PMC - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources