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Comment
. 2016 Jun 1;124(6):A113.
doi: 10.1289/ehp.124-A113.

Making Sense of Carcinogens: A New Method for Navigating Mechanistic Data

Carol Potera
Comment

Making Sense of Carcinogens: A New Method for Navigating Mechanistic Data

Carol Potera. Environ Health Perspect. .
No abstract available

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Figures

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This flow chart shows how 1,841 mechanistic studies on benzene were assessed and categorized. (“Section 4” refers to the section of IARC Monographs where mechanistic data are discussed). For the sake of illustration, the authors indicated the number of human studies only for those characteristics for which more than 100 studies were identified. For 2 of the characteristics—chronic inflammation and immortalization—all of the identified studies were either null or inconclusive. The other 8 characteristics were deemed likely mechanisms for benzene. Source: Smith et al. (2016)
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References

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