Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters
- PMID: 27251100
- DOI: 10.1021/acs.chemrev.6b00094
Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters
Abstract
This Review summarizes the advances in the construction of all-carbon quaternary stereocenters via catalytic enantioselective desymmetrization of prochiral and meso-compounds, highlights the power and potential of this strategy in the total synthesis of natural products and biologically active compounds, and outlines the synthetic opportunities still available.
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