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Review
. 2016 Jun 22;116(12):7330-96.
doi: 10.1021/acs.chemrev.6b00094. Epub 2016 Jun 2.

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

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Review

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

Xing-Ping Zeng et al. Chem Rev. .

Abstract

This Review summarizes the advances in the construction of all-carbon quaternary stereocenters via catalytic enantioselective desymmetrization of prochiral and meso-compounds, highlights the power and potential of this strategy in the total synthesis of natural products and biologically active compounds, and outlines the synthetic opportunities still available.

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