Engineering Paper-Based Sensors for Zika Virus
- PMID: 27255410
- DOI: 10.1016/j.molmed.2016.05.009
Engineering Paper-Based Sensors for Zika Virus
Abstract
The emergence of Zika virus (ZIKV) infections in Latin America and Southeast Asia has created an urgent need for new, simple, yet sensitive, diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect ZIKV RNA as a new approach to achieve rapid development and deployment of field-ready diagnostics for emerging infectious diseases.
Keywords: CRISPR/Cas9; emerging infectious diseases; molecular diagnostics; paper microfluidics; toehold sensors.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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Rapid, Low-Cost Detection of Zika Virus Using Programmable Biomolecular Components.Cell. 2016 May 19;165(5):1255-1266. doi: 10.1016/j.cell.2016.04.059. Epub 2016 May 6. Cell. 2016. PMID: 27160350
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