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Comment
. 2016 Jul;22(7):529-530.
doi: 10.1016/j.molmed.2016.05.009. Epub 2016 May 30.

Engineering Paper-Based Sensors for Zika Virus

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Engineering Paper-Based Sensors for Zika Virus

Robert J Meagher et al. Trends Mol Med. 2016 Jul.

Abstract

The emergence of Zika virus (ZIKV) infections in Latin America and Southeast Asia has created an urgent need for new, simple, yet sensitive, diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect ZIKV RNA as a new approach to achieve rapid development and deployment of field-ready diagnostics for emerging infectious diseases.

Keywords: CRISPR/Cas9; emerging infectious diseases; molecular diagnostics; paper microfluidics; toehold sensors.

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