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Review
. 2016 Oct;18(10):595-603.
doi: 10.1016/j.micinf.2016.05.006. Epub 2016 May 30.

Rab32/38 and the xenophagic restriction of intracellular bacteria replication

Bor Luen Tang  1
Affiliations
Free article
Review

Rab32/38 and the xenophagic restriction of intracellular bacteria replication

Bor Luen Tang. Microbes Infect. 2016 Oct.
Free article

Abstract

Rab GTPases' subversion by intracellular pathogens during infection has been extensively documented. Recent findings have implicated a key intracellular bacterial restriction/containment function for Rab32/38 in Salmonella species in macrophages and Listeria monocytogenes in dendritic cells. Rab32/38 aids the phagolysosome maturation, and mediates a parallel xenophagy mechanism by engaging prohibitins.

Keywords: Bacteria-containing vacuole; Listeria; Prohibitin; Rab; Salmonella; Xenophagy.

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