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. 2016 Jun 2;165(6):1314-1315.
doi: 10.1016/j.cell.2016.05.066.

A Pro-metastatic tRNA Pathway

Canan Kuscu  1 , Anindya Dutta  2
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A Pro-metastatic tRNA Pathway

Canan Kuscu et al. Cell. .
Free article

Abstract

tRNAs are best known as basic modules for global regulation of protein synthesis. Goodarzi et al. now show that two tRNAs upregulated in metastatic breast cancer cells enhance stability and translation of transcripts enriched with these codons, leading to specific increase in production of pro-metastatic proteins.

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