Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Apr 10;98(3):272-5.
doi: 10.1016/0304-3940(89)90412-6.

c-Fos mRNA induction under vitamin B6 antagonist-induced seizure

A Mizuno  1 , T Mizobuchi, Y Ishibashi, M Matsuda
Affiliations

c-Fos mRNA induction under vitamin B6 antagonist-induced seizure

A Mizuno et al. Neurosci Lett. .

Abstract

c-Fos mRNA expression was studied in mouse brain after vitamin B6 antagonist-induced seizure. The vitamin B6 antagonists used were hydrazine, thiosemicarbazide, penicillamine and deoxypyridoxine. Only deoxypyridoxine was effective in increasing c-fos mRNA and c-fos protein expression in nerve cells. The other 3 antagonists had levels of c-fos mRNA below or equal to basal level. The seizure activity induced by several vitamin B6 antagonists resulted in different effects on c-fos gene expression.

PubMed Disclaimer

LinkOut - more resources