Isolation and genetic characterization of swinepox virus from pigs in India
- PMID: 27260812
- DOI: 10.1016/j.cimid.2016.04.001
Isolation and genetic characterization of swinepox virus from pigs in India
Abstract
Swinepox virus (SWPV), a member of the genus Suipoxvirus causes generalized pock-like lesions on the body of domestic and wild pigs. Although outbreak has been reported in India since 1987, virus isolation and genetic characterization remained elusive. In September 2013, an outbreak of acute skin infection occurred in piglets in a commercial piggery unit at Rohtak district in Haryana, India. The presence of SWPV in scab samples collected from piglets succumbed to infection was confirmed by virus isolation, PCR amplification of SWPV-specific gene segments and nucleotide sequencing. Phylogenetic analysis of host-range genes of the SWPV revealed that the Indian isolate is genetically closely related to reference isolate SWPV/pig/U.S.A/1999/Nebraska. To the best of our knowledge this is the first report on isolation and genetic characterization of SWPV from pigs in India.
Keywords: Ankyrin- repeat protein; Extracellular enveloped protein; Host-range genes; Kelch-like protein; Swinepox virus.
Copyright © 2016 Elsevier Ltd. All rights reserved.
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