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. 2016 Jan-Feb;56(1):22-7.
doi: 10.1016/j.rbre.2015.07.013. Epub 2015 Sep 4.

Quality of life in spondyloarthritis: analysis of a large Brazilian cohort

[Article in English, Portuguese]
Sandra L E Ribeiro  1 , Elisa N Albuquerque  2 , Adriana B Bortoluzzo  3 , Célio R Gonçalves  4 , José Antonio Braga da Silva  5 , Antonio Carlos Ximenes  6 , Manoel B Bértolo  7 , Mauro Keiserman  8 , Rita Menin  9 , Thelma L Skare  10 , Sueli Carneiro  11 , Valderílio F Azevedo  12 , Walber P Vieira  13 , Washington A Bianchi  14 , Rubens Bonfiglioli  15 , Cristiano Campanholo  16 , Hellen M S Carvalho  17 , Izaias P Costa  18 , Angela L B Pinto Duarte  19 , Charles L Kohem  20 , Nocy H Leite  21 , Sonia A L Lima  22 , Eduardo S Meirelles  23 , Ivânio A Pereira  24 , Marcelo M Pinheiro  25 , Elizandra Polito  26 , Gustavo G Resende  27 , Francisco Airton C Rocha  28 , Mittermayer B Santiago  29 , Maria de Fátima L C Sauma  30 , Valéria Valim  31 , Percival D Sampaio-Barros  32 ; Brazilian Registry of Spondyloarthritis
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Free article

Quality of life in spondyloarthritis: analysis of a large Brazilian cohort

[Article in English, Portuguese]
Sandra L E Ribeiro et al. Rev Bras Reumatol Engl Ed. 2016 Jan-Feb.
Free article

Abstract

Objective: To analyze quality of life and demographic and clinical variables associated to its impairment in a large Brazilian cohort of patients with spondyloarthritis (SpA).

Methods: A common protocol of investigation was applied to 1465 Brazilian patients classified as SpA according to the European Spondyloarthropaties Study Group (ESSG) criteria, attended at 29 reference centers for Rheumatology in Brazil. Clinical and demographic variables were recorded. Quality of life was analyzed through the Ankylosing Spondylitis Quality of Life (ASQoL) questionnaire.

Results: The mean ASQoL score was 7.74 (+5.39). When analyzing the specific diseases in the SpA group, the ASQoL scores did not present statistical significance. Demographic data showed worse scores of ASQoL associated with female gender (p=0.014) and African-Brazilian ethnicity (p<0.001). The analysis of the clinical symptoms showed that buttock pain (p=0.032), cervical pain (p<0.001) and hip pain (p=0.001) were statistically associated with worse scores of ASQoL. Continuous use of nonsteroidal anti-inflammatory drugs (p<0.001) and biologic agents (p=0.044) were associated with higher scores of ASQoL, while the other medications did not interfere with the ASQoL scores.

Conclusion: In this large series of patients with SpA, female gender and African-Brazilian ethnicity, as well as predominant axial symptoms, were associated with impaired quality of life.

Keywords: ASQoL; Ankylosing spondylitis; Espondilite anquilosante; Espondiloartrite; Qualidade de vida; Quality of life; Spondyloarthritis.

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