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. 1989 May;86(10):3857-61.
doi: 10.1073/pnas.86.10.3857.

Construction and use of a replication-competent human immunodeficiency virus (HIV-1) that expresses the chloramphenicol acetyltransferase enzyme

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Construction and use of a replication-competent human immunodeficiency virus (HIV-1) that expresses the chloramphenicol acetyltransferase enzyme

E F Terwilliger et al. Proc Natl Acad Sci U S A. 1989 May.

Abstract

The construction and properties of an infectious human immunodeficiency virus (HIV) that expresses the bacterial gene chloramphenicol acetyltransferase are described. This virus can be used in vitro to screen for drugs that inhibit HIV infection. The marked virus may also be used to trace the routes of infection from the site of inoculation in animal experiments.

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References

    1. Proc Natl Acad Sci U S A. 1984 Jul;81(13):4149-53 - PubMed
    1. Proc Natl Acad Sci U S A. 1984 Jun;81(12):3856-60 - PubMed
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    1. N Engl J Med. 1984 Nov 15;311(20):1292-7 - PubMed
    1. Nature. 1985 Feb 7-13;313(6002):450-8 - PubMed

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