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Randomized Controlled Trial
. 2016 Jun 7:17:250.
doi: 10.1186/s12891-016-1115-7.

The PLE(2)NO self-management and exercise program for knee osteoarthritis: Study Protocol for a Randomized Controlled Trial

Priscila Marconcin  1   2 , Margarida Espanha  3 , Flávia Yázigi  4 , Pedro Campos  3
Affiliations
Randomized Controlled Trial

The PLE(2)NO self-management and exercise program for knee osteoarthritis: Study Protocol for a Randomized Controlled Trial

Priscila Marconcin et al. BMC Musculoskelet Disord. .

Abstract

Background: International recommendations suggest exercise and self-management programs, including non-pharmacological treatments, for knee osteoarthritis (KOA) because they can benefit pain relief and improve function and exercise adherence. The implementation of a combined self-management and exercise program termed PLE(2)NO may be a good method for controlling KOA symptoms because it encourages the development of self-efficacy to manage the pathology. This study will assess the effects of a self-management and exercise program in comparison to an educational intervention (control program) on symptoms, physical fitness, health-related quality of life, self-management behaviors, self-efficacy, physical activity level and coping strategies.

Methods/design: This PLE(2)NO study is a single-blinded, randomized controlled trial of elderly (aged above 60 yrs old) patients with clinical and radiographic KOA. The patients will be allocated into either an educational group (control) or a self-management and exercise group (experimental). All participants will receive a supplement of chondroitin and glucosamine sulfates. This paper describes the protocol that will be used in the PLE(2)NO program.

Discussion: This program has several strengths. First, it involves a combination of self-management and exercise approaches, is available in close proximity to the patients and occurs over a short period of time. The latter two characteristics are crucial for maintaining participant adherence. Exercise components will be implemented using low-cost resources that permit their widespread application. Moreover, the program will provide guidance regarding the effectiveness of using a self-management and exercise program to control KOA symptoms and improve self-efficacy and health-related quality of life.

Trial registration: NCT02562833 (09/23/2015).

Keywords: Elderly; Exercise; Knee osteoarthritis; Self-management.

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Figures

Fig. 1
Fig. 1
The PLE2NO flowchart
See this image and copyright information in PMC

References

    1. Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II. Arthritis Rheum. 2008;58(1):26–35. doi: 10.1002/art.23176. - DOI - PMC - PubMed
    1. Sangha O. Epidemiology of rheumatic diseases. Rheumatology. 2000;39(suppl 2):3–12. doi: 10.1093/rheumatology/39.suppl_2.3. - DOI - PubMed
    1. Heidari B. Knee osteoarthritis prevalence, risk factors, pathogenesis and features: Part I. Caspian J Intern Med. 2011;2(2):205–12. - PMC - PubMed
    1. Helmick CG, Felson DT, Lawrence RC, Gabriel S, Hirsch R, Kwoh CK, et al. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part I. Arthritis Rheum. 2008;58(1):15–25. doi: 10.1002/art.23177. - DOI - PubMed
    1. Peat G, McCarney R, Croft P. Knee pain and osteoarthritis in older adults: a review of community burden and current use of primary health care. Ann Rheum Dis. 2001;60(2):91–7. doi: 10.1136/ard.60.2.91. - DOI - PMC - PubMed

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