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Editorial
. 2016 Aug;48(2):141-7.
doi: 10.1002/uog.15987.

Fetoscopic repair of spina bifida: safer and better?

D A L Pedreira  1 , E A Reece  2 , R H Chmait  3 , E V Kontopoulos  4   5 , R A Quintero  5
Affiliations
Editorial

Fetoscopic repair of spina bifida: safer and better?

D A L Pedreira et al. Ultrasound Obstet Gynecol. 2016 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Surgical pathology analysis of lesion in a fetus which underwent prenatal correction of a meningomyelocele‐like defect using human acellular dermal matrix (HADM). (a) HADM adhered to skin (blue arrow) and to neural tissue (black arrow) (hematoxilin‐eosin stain; original magnification, × 16). (b) Magnification of the square section outlined in part (a), showing ingrowth of cells from the medulla (black arrow) into the HADM (hematoxilin‐eosin stain; original magnification, × 100). Reproduced with permission from Sanchez e Oliveira et al. 29.
Figure 2
Figure 2
Surgical pathology specimens of fetal sheep medulla after repair of a spinal defect using two different techniques. (a,c,e) Standard neurosurgical multilayer repair: arrows show adherence of medullar tissue to the scar (meningoneural adhesion). (b,d,f) Skin‐over‐biocellulose technique using biosynthetic cellulose. Images show preservation of the medullar architecture; dashed lines outline the gray matter. Note absence of this line in the neurosurgical group, indicating disruption of the medullary tissue. Reproduced with permission from Herrera et al. 35.
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References

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