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Review
. 2016;12(3):186-94.
doi: 10.2174/1573403x12666160606120958.

Chronic Heart Failure and Comorbid Renal Dysfunction - A Focus on Type 2 Cardiorenal Syndrome

Jois Preeti, Mebazaa Alexandre, Iyngkaran Pupalan, Thomas C Merlin, Ronco Claudio  1
Affiliations
Review

Chronic Heart Failure and Comorbid Renal Dysfunction - A Focus on Type 2 Cardiorenal Syndrome

Jois Preeti et al. Curr Cardiol Rev. 2016.

Abstract

The most important advancements in the Cardiorenal syndrome (CRS) are its definition and subsequent classifications. When the predominant pathology and pathophysiology is the heart, i.e. chronic heart failure (CHF), and where any renal impairment (RI) subsequent to this is secondary, the classification is type 2 CRS. There are unique differences in the pathophysiology and progression of individual subclasses. It is important to understand the evolution of CHF and consequences of subsequent RI as they are becoming increasingly prevalent, aggravate morbidity and mortality and limit many therapeutic options. In this paper we discuss the significance of the type 2 CRS patients in the context of the thematic series.

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Figures

Fig. (1)
Fig. (1)
CHF pathophysiology.
Fig. (2)
Fig. (2)
Predominant pathophysiologic mechanisms of CRS2 in stable chronic HF. Reproduced with permission from ADOI [62].
See this image and copyright information in PMC

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MeSH terms