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. 2016 Dec;18(12):1312-1314.
doi: 10.1038/gim.2016.63. Epub 2016 Jun 9.

A knowledge base for tracking the impact of genomics on population health

Wei Yu  1 , Marta Gwinn  1   2 , W David Dotson  1 , Ridgely Fisk Green  1   3 , Mindy Clyne  4   5 , Anja Wulf  1   6 , Scott Bowen  1 , Katherine Kolor  1 , Muin J Khoury  1
Affiliations

A knowledge base for tracking the impact of genomics on population health

Wei Yu et al. Genet Med. 2016 Dec.

Abstract

Purpose: We created an online knowledge base (the Public Health Genomics Knowledge Base (PHGKB)) to provide systematically curated and updated information that bridges population-based research on genomics with clinical and public health applications.

Methods: Weekly horizon scanning of a wide variety of online resources is used to retrieve relevant scientific publications, guidelines, and commentaries. After curation by domain experts, links are deposited into Web-based databases.

Results: PHGKB currently consists of nine component databases. Users can search the entire knowledge base or search one or more component databases directly and choose options for customizing the display of their search results.

Conclusion: PHGKB offers researchers, policy makers, practitioners, and the general public a way to find information they need to understand the complicated landscape of genomics and population health.Genet Med 18 12, 1312-1314.

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Figures

Figure 1
Figure 1
Results of a search performed on 24 April 2016 for breast cancer information using the Public Health Genomics Knowledge Base.
See this image and copyright information in PMC

References

    1. National Institutes of Health Precision Medicine Initiative Cohort Program. https://www.nih.gov/precision-medicine-initiative-cohort-program. Accessed 20 January 2016.
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    1. Clyne M, Schully SD, Dotson WD, et al. Horizon scanning for translational genomic research beyond bench to bedside. Genet Med. 2014;16:535–538. - PMC - PubMed

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