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. 2016 Oct;71(10):1496-500.
doi: 10.1111/all.12957. Epub 2016 Jul 20.

Atopic dermatitis is not independently associated with nonfatal myocardial infarction or stroke among US women

A M Drucker  1   2   3 , W-Q Li  1   4 , E Cho  1   4   5 , T Li  5 , Q Sun  5   6 , C A Camargo Jr  5   7   8 , A A Qureshi  9   10   11   12
Affiliations

Atopic dermatitis is not independently associated with nonfatal myocardial infarction or stroke among US women

A M Drucker et al. Allergy. 2016 Oct.

Abstract

We aimed to determine the association between atopic dermatitis (AD) and cardiovascular events in the Nurses' Health Study 2, a cohort of US women. We used logistic regression models to calculate age- and multivariate-adjusted odds ratios (OR) and 95% confidence intervals (CI) for the associations between history of AD and nonfatal MI and nonfatal stroke. Of the 78 702 participants in our analysis, 7916 (10%) had a history of AD. There were 392 and 391 cases of nonfatal MI and stroke, respectively. AD was not associated with MI in age- or multivariate-adjusted analyses. AD was significantly associated with stroke in the age-adjusted analysis (OR 1.38, 95% CI 1.03-1.85). This was no longer significant in multivariate models that adjusted for hypertension, hypercholesterolemia and diabetes (OR 1.31, 95% CI 0.98-1.76) and atopic comorbidities (OR 1.17, 95% CI 0.86-1.58). AD was not independently associated with nonfatal MI or stroke in this study.

Keywords: atopic dermatitis; cardiovascular disease; comorbidity; myocardial infarction; stroke.

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