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. 2016 Dec;15(4):e193-e198.
doi: 10.1016/j.clcc.2016.04.006. Epub 2016 May 7.

Surgical and Oncologic Outcomes After Major Liver Surgery and Extended Hemihepatectomy for Colorectal Liver Metastases

Inge Ubink  1 , Jennifer M J Jongen  1 , Maarten W Nijkamp  1 , Eelco F J Meijer  1 , Thomas T Vellinga  1 , Richard van Hillegersberg  1 , I Quintus Molenaar  1 , Inne H M Borel Rinkes  1 , Jeroen Hagendoorn  2
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Free article

Surgical and Oncologic Outcomes After Major Liver Surgery and Extended Hemihepatectomy for Colorectal Liver Metastases

Inge Ubink et al. Clin Colorectal Cancer. 2016 Dec.
Free article

Abstract

Purpose: To determine the surgical and oncologic outcomes after major liver surgery for colorectal liver metastases (CRLM) at a Dutch University Hospital.

Patients and methods: Consecutive patients with CRLM who had undergone major liver resection, defined as ≥ 4 liver segments, between January 2000 and December 2015 were identified from a prospectively maintained database.

Results: Major liver surgery was performed in 117 patients. Of these, 26 patients had undergone formal extended left or right hemihepatectomy. Ninety-day postoperative mortality was 8%. Major postoperative complications occurred in 27% of patients; these adverse events were more common in the extended hemihepatectomy group. Median disease-free survival was 11 months and median overall survival 44 months.

Conclusion: Major liver surgery, including formal extended hemihepatectomy, is associated with significant operative morbidity and mortality but can confer prolonged overall survival for patients with CRLM.

Keywords: Colorectal cancer; Hepatectomy; Metastasis; Morbidity; Survival.

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