Gliomas "Dope Up" for Growth
- PMID: 27300432
- DOI: 10.1016/j.ccell.2016.05.010
Gliomas "Dope Up" for Growth
Abstract
An emerging body of data highlights trophic functions of neurotransmitters on proliferation and differentiation of normal neural progenitors. In this issue of Cancer Cell, Dolma et al. document pro-survival functions of a neurotransmitter receptor in glioma progenitor cells, with practical overtones for therapy.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.Cancer Cell. 2016 Jun 13;29(6):859-873. doi: 10.1016/j.ccell.2016.05.002. Cancer Cell. 2016. PMID: 27300435 Free PMC article.
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