Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2016 Apr;7(2):159-64.
doi: 10.15412/J.BCN.03070209.

Iatrogenic Seeding of Tumor Cells in Thigh Soft Tissue Upon Surgical Removal of Intracranial Meningioma

Ghodratollah Maddah  1 , Hossein Shabahang  1 , Vahid Zehi  1 , Nouriyeh Sharifi Sistani  2 , Hossein Mashhadi Nejad  3
Affiliations
Case Reports

Iatrogenic Seeding of Tumor Cells in Thigh Soft Tissue Upon Surgical Removal of Intracranial Meningioma

Ghodratollah Maddah et al. Basic Clin Neurosci. 2016 Apr.

Abstract

Introduction: Meningioma is a benign and slowly-growing tumor that is responsible for 20% of brain neoplasms. It can be accompanied by some genetic disorders such as neurofibromatosis type 2 and is more common among women. As a space occupying lesion, it produces a wide range of signs and symptoms by compressing the adjacent and underlying tissues in the brain. Trauma and viruses are possible etiologies for meningioma. The ideal treatment of benign meningioma is surgical resection.

Case presentation: In this case report, we present a middle-aged man with a seeding metastasis of the cranial meningioma (after its removal) in the left thigh. During the removal operation, fascia lata had been used to repair the dura mater and the skin defect was repaired primarily.

Conclusion: We believe that the occurrence of meningioma at the site of incision in the thigh is related to using the same surgical instruments for the removal of the brain tumor.

Keywords: Implantation; Meningioma; Seeding.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
CT scanning image showing a space occupying lesion in the parietal zone of the left hemisphere (April 2001).
Figure 2.
Figure 2.
Reconstruction by performing a split thickness graft from the other tigh (July 2007).
Figure 3.
Figure 3.
This figure shows post resection defect of the left tigh (July 2007).
Figure 4a._Figure 4b.
Figure 4a._Figure 4b.
Microscopic views show fibrofatty and muscle tissue with nests of meningioma by round to oval benign nuclei and syncytial acidophil cytoplasm with whorle pattern (H & E staining 400 #) (August 2007).
See this image and copyright information in PMC

References

    1. Abboud M., Haddad G., Kattar M., Aburiziq I., Geara F. B. ( 2009). Extraneural metastases from cranial meningioma: A case report. Radiation Oncology, 4, 20. - PMC - PubMed
    1. Akai T., Shiraga S., Iizuka H., Kishibe M., Kawakami S., Ueda Y. ( 2004). Recurrent meningioma with metastasis to the skin incision-case report. Neurologia Medico-chirurgica (Tokyo), 44( 11), 600– 602. - PubMed
    1. Erkutlu I., Buyukhatipoglu H., Alptekin M., Berkyurek E., Tutar E., Gok A. ( 2009). Spinal drop metastases from a papillary meningioma: A case report and review of the literature: Utility of CSF sampling. Medical Oncology, 26( 2), 242– 246. - PubMed
    1. Ichikawa M., Saito K., Ito E., Kawai K., Fujimoto Y., Kamei Y. ( 2010). Iatrogenic drop metastasis of recurrent meningioma in a vascularized free omental flap-case report. Neurologia Medico-chirurgica (Tokyo), 50( 1), 70– 73. - PubMed
    1. Lee T. T., Landy H. J. ( 1998). Spinal metastases of malignant intracranial meningioma. Surgical Neurology, 50( 5), 437– 441. - PubMed

Publication types

LinkOut - more resources