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. 2016 Jun 14;23(6):961-962.
doi: 10.1016/j.cmet.2016.05.016.

Exercise Has a Bone to Pick with Skeletal Muscle

Frank W Booth  1 , Gregory N Ruegsegger  2 , T Dylan Olver  2
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Free article

Exercise Has a Bone to Pick with Skeletal Muscle

Frank W Booth et al. Cell Metab. .
Free article

Abstract

Exercise intolerance and poor exercise capacity are associated with aging, diabetes, cognitive impairment, and premature death. In this issue of Cell Metabolism, Mera et al. (2016) report that osteocalcin improves endurance exercise performance by enhancing myofiber fuel uptake and utilization, while osteocalcin supplementation reverses the age-induced decline in endurance exercise performance.

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